Meibomian glands

How does it work

System analysis of the images is obtained through a sensitive infrared camera (NIR) in order to locate in a guided way:
• The position detected from the image, valid both for the upper and lower eyelid,
• Percentage of the loss area of meibomian glands, to know the presence/absence of them,
• Grading scale to classify the status in 4 different degrees (0-25% green, 25-50% yellow, 50-75% orange, 75-100% red),

Otherwise, through the automatic detection it is possible to classify the captured image in a customizable way according to the precise percentage relating to the patient.

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Meibography

It serves to build the morphology, diagnosis and drop out of the meibomian glands.
Meiboscopy is the visualization of the glands through trans-illumination of the eyelid with infrared light.
The software allows to analyze the working and not working areas, and to compare the glands of the patient with the diagnostic evaluation scales.
These glands produce oily lipid substances that are released to the eyelid margins reaching the tear film thanks to eyelid winks. Oily lipid substances float on the surface of the tear film and reduce evaporation.

The MGD alters lipid component of the tear film and this can cause the appearance of dry eye with its characteristic symptoms. In severe cases, the MGD can also cause inflammation of the eyelids called blepharitis rear edge.

Analysis

Automatic detection of meibomian glands

ICP MGD can, with a good quality of image, in a guided way detect the length and width of meibomian glands imaged by infrared meibography without requiring any input from the user.
The images are then automatically classified.
The analysis of the glands happens in an automatic way thanks to the advanced recognition software that studies the eyelid through the use of dedicated filters in real time after the acquisition.

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Meibomian gland dysfunction (MGD) may well be the leading cause of dry eye disease throughout the world 

MGD is a chronic, diffuse abnormality of the meibomian glands, commonly characterized by terminal duct obstruction and/or qualitative/quantitative changes in the glandular secretion. It may result in alteration of the tear film, symptoms of eye irritation, clinically apparent inflammation, and ocular surface disease. In a few seconds the device allows to take photo with high resolution in infrared vision making visible in every environmental condition the presence/absence of the glands on the eyelids.

ICP MGD
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Problematic evaluation of the dry eye 

For dry eye diagnosis are recommended a series of exams:
• Measurement of the blinking frequency and calculation of the inter blink interval
• Measurement of the height of the lower tear meniscus
• Measurement of the tear osmolarity (if available)
• Calculation of the tear film break up time (TFBUT) and the index of ocular protection (OPI)
• Classification of the corneal and conjunctival coloration with fluorescein
• Schirmer Test
• Phenol red test
• Quantification of the morphological characteristics of eyelids
• Squeezing: quantification of the squeezability and of the quality of the lipid component
• Meibography: quantification of atrophy.

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